THIS IS BEPO®
FOR A NEW GENERATION
OF TREATMENT

 
 

A GAME-CHANGING DELIVERY SYSTEM FOR LONG-ACTING INJECTABLES

BEPO® is a simple yet flexible technology. Based on our custom proprietary copolymers and a biocompatible solvent (where the API is solubilized or suspended), BEPO® forms a fully bioresorbable depot once injected.

The BEPO® technology makes it possible to control and guarantee the regular delivery of a drug at the optimal therapeutic dose for several days, weeks or months starting from the subcutaneous or local injection of a simple deposit of a few millimeters, fully bioresorbable

BEPO® can be administered subcutaneously for systemic exposure of APIs or locally for targeted treatments.

How it works

BEPO® copolymers

Diblock
Copolymers (DB)

Triblock
Copolymers (TB)

 
 

BEPO® inside

BEPO® is composed of a solution of diblock (DB) and triblock (TB) copolymers containing hydrophilic and water-soluble blocks (polyethylene glycol – PEG) linked with hydrophobic and amorphous blocks (Poly(D,L-lactic acid) – PLA) which precipitate in forming a depot when exposed to an aqueous environment. The API is entrapped within the polymer matrix and is released thereafter by difusion and following polymer degradation. The hygroscopy and consequently the API release kinetics from the depots can be fine tuned by adjusting the hydrophilicity of the DB and TB and their relative ratio.

PEG

PEG (polyethylene glycol) block
• Also known as polyethylene oxide (PEO)
• Commercially available over a wide range of MW
• Hydrophilic, water soluble

PLA

• PLA block
• Poly (D,L-lactic acid) or poly (D,L-lactide)
• Prepared by polymerization (ROP) of cyclic (D,L)-lactide monomer
• Amorphous, hydrophobic
• Biodegradable macromolecule (through hydrolysis)

BEPO® copolymers

Diblock
Copolymers (DB)

Triblock
Copolymers (TB)

 
 

A FLEXIBLE TECHNOLOGY

The possibility of fine-tuning all of BEPO’s® components gives us the opportunity to truly tailor products, able to fit the therapeutic needs of the patient.

Products

 
 

We’re always looking for new talent

Careers

The people of MedinCell aren’t just creating life-sustaining products, their aim is to revolutionize the patient’s way of life. Interested in being part of a self-funded, employee owned, creative workplace?

See our job opportunities and apply

CONTACT

  • This field is for validation purposes and should be left unchanged.